Let’s compare real‑world experience with once‑weekly agents versus classic daily somatropin: convenience and adherence, IGF‑1 stability and well‑being swings, edema and carpal tunnel, plus body‑composition effects under matched diet and training. Please share cases of switching between daily and weekly regimens, which markers were monitored (IGF‑1, glucose/HbA1c), and how “peaks” and “plateaus” were handled. Discussion should remain legal and safety‑focused, without dosing schemes or advice on bypassing prescription requirements.